Marques, Silvio Alencar [UNESP]2014-05-202014-05-202010-05-01Dermatologic Therapy. Malden: Wiley-blackwell, v. 23, n. 3, p. 243-250, 2010.1396-0296http://hdl.handle.net/11449/11698A clinical review of three potentially severe fungal diseases, which are characterized in many cases by mucosal involvement, is presented. They are paracoccidioidomycosis, histoplasmosis, and mucormycosis. Mucosal involvement for paracoccidioidomycosis and rhinocerebral mucormycosis is frequent. Thus, oral involvement may provide early clue for diagnosis. In paracoccidioidomycosis, the mucosal lesion classically shows superficial ulcers with granular appearance and hemorrhagic points, usually on lips, palate, and jugal mucosa. In mucormycosis, necrosis of the palate followed for purulent discharge is a hallmark of rhinocerebral disease. Treatment with amphotericin B desoxycholate or the new second-generation triazoles is highly efficacious.243-250engfungal infectionshistoplasmosismucormycosismucous membraneparacoccidioidomycosistreatmentArtigo10.1111/j.1529-8019.2010.01321.xWOS:000277974300005Acesso restrito8789480458377552