Oliveira-Junior, Silvio A.Boullosa, DanielMendonça, Maria L. M.Vieira, Larissa F. C.Mattos, Wania W.Amaral, Bruna O. C.Lima-Borges, Dayanne S.Reis, Filipe A.Cezar, Marcelo D. M.Vanderlei, Luiz C. M. [UNESP]Martinez, Paula F.2021-06-252021-06-252021-05-01International Journal of Environmental Research and Public Health, v. 18, n. 9, 2021.1660-46011661-7827http://hdl.handle.net/11449/207934Sedentary behaviors, those that involve sitting and low levels of energy expenditure, have been associated with several adverse cardiometabolic effects. This study evaluated the chronic effects of a combined circuit weight interval training (CWIT) on physical fitness, quality of life, and heart rate variability (HRV), and compared the effects of CWIT-induced autonomic adaptations on different postures in adult sedentary workers. Twenty-seven sedentary workers (age 36.9 ± 9.2 years old, 13 men and 14 women) were divided into two groups: control, who continued their sedentary behavior, and experimental, who were submitted to a CWIT for 12 weeks, completing two ~40 min sessions per week. Monitoring of 8th, 16th, and 24th sessions revealed a moderate training load during sessions. Participants exhibited an improved aerobic capacity (VO2 max, 34.03 ± 5.36 vs. 36.45 ± 6.05 mL/kg/min, p < 0.05) and flexibility (22.6 ± 11.4 vs. 25.3 ± 10.1 cm, p < 0.05) after the training period. In addition, they showed greater quality of life scores. However, the CWIT did not change body composition. Interestingly, more HRV parameters were improved in the seated position. The CWIT used in the current study was associated with improvements in several fitness and quality of life parameters, as well as in cardiac autonomic control of HR in adult sedentary workers. Examination of different body positions when evaluating changes in HRV appears to be a relevant aspect to be considered in further studies. Future randomized controlled trials (RCTs) with larger samples of both sexes should confirm these promising results.engAutonomic modulationExercisePhysical fitnessQuality of lifeSedentary behaviorArtigo10.3390/ijerph180946062-s2.0-85104573772