Allele frequency of hereditary equine regional dermal asthenia in American Quarter horses in Brazil determined by quantitative real-time PCR with high resolution melting analysis

Badial, Peres R. [UNESP]Oliveira-Filho, Jose P. [UNESP]Winand, Nena J.Borges, Alexandre Secorun [UNESP]2014-12-032014-12-032014-02-01Veterinary Journal. Oxford: Elsevier Sci Ltd, v. 199, n. 2, p. 306-307, 2014.1090-0233http://hdl.handle.net/11449/111650Hereditary equine regional dermal asthenia (HERDA) is a genetic disorder that occurs in the American Quarter horse (AQH) and is caused by a c.115G>A missense mutation in the peptidylprolyl isomerase B (PPIB) gene. Using a quantitative real-time PCR high resolution melting analysis genotyping assay for the PPIB mutation, the estimated HERDA allele and carrier frequencies in a sample of Brazilian AQHs were 2.9% and 5.8%, respectively. (C) 2013 Elsevier Ltd. All rights reserved.306-307engHereditary equine regional dermal astheniaCyclophilin BGenotypingQuantitative real-time PCRHigh resolution melting analysisAllele frequency of hereditary equine regional dermal asthenia in American Quarter horses in Brazil determined by quantitative real-time PCR with high resolution melting analysisArtigo10.1016/j.tvjl.2013.11.008WOS:000331918700022Acesso restrito9643433706163946