Bück, A.Casciatori, F. P. [UNESP]Thoméo, J. C. [UNESP]Tsotsas, E.2018-12-112018-12-112015-01-01Procedia Engineering, v. 102, p. 362-371.1877-7058http://hdl.handle.net/11449/168214Solid-state fermentation is gaining increasing importance for the production of high-added value products, for instance enzymes, from agro-industrial by-products. The main difficulty in operating this process in packed-bed bioreactors is the development of temperature and moisture gradients along the reactor length which decrease the overall productivity. In this work a practically relevant feedback control scheme is developed that allows influencing and equalizing the moisture and temperature distributions along the packed-bed bioreactor during solid-state fermentation. This prevents locally critical process conditions which may necessitate the shutdown of the operation of the bioreactor.362-371engdistributed parameter systemdryingfeedback controlheat and mass transfersolid-state fermentationTrabalho apresentado em evento10.1016/j.proeng.2015.01.163Acesso aberto2-s2.0-84950119863