Martinez, Marina B.Whittan, Thomas S.McGraw, Elizabeth A.Rodrigues, Josias [UNESP]Trabulsi, Luiz R.2014-05-272014-05-271999-03-15FEMS Microbiology Letters, v. 172, n. 2, p. 145-151, 1999.0378-1097http://hdl.handle.net/11449/65742The genetic relatedness among 96 invasive Escherichia coli belonging to several serogroups and 13 non-invasive of several serotypes that share the same O antigen was investigated by multilocus enzyme electrophoresis analysis. The invasive strains were isolated in different parts of the world and most of them recovered from dysentery. Twenty-nine electrophoretic types were distinguished and the most invasive strains were found to belong to two major lineages. These results suggested that the invasive ability in these strains has evolved in divergent chromosomal backgrounds, presumably through the horizontal spread of plasmid-borne invasion genes. The maintenance of invasive phenotypes in separate lineages suggests that this ability confers a selective advantage to invasive strains. Copyright (C) 1999 Federation of European Microbiological Societies.145-151engClonal relationshipEnteroinvasive Escherichia coliGenetic polymorphismMultilocus enzyme electrophoresiso antigencell invasiondiarrheaelectrophoresisescherichia coligenetic analysisgenetic distancegenetic polymorphismhumannonhumanphylogenypriority journalserotypeDysenteryElectrophoresis, Starch GelEscherichia coliHumansPhenotypePolymorphism, GeneticSequence Analysis, DNASerotypingArtigo10.1016/S0378-1097(99)00031-2WOS:000079108100006Acesso aberto2-s2.0-00330038832-s2.0-0033003883.pdf4211432128816409