Marques, Silvio Alencar [UNESP]Camargo, Rosangela Maria Pires de [UNESP]Silvares, Maria Regina Cavariani [UNESP]Marques, Mariângela Esther Alencar [UNESP]2014-05-272014-05-272013-05-01Anais Brasileiros de Dermatologia, v. 88, n. 3, p. 420-423, 2013.0365-05961806-4841http://hdl.handle.net/11449/75279Histoplasmosis is a systemic mycosis endemic in extensive areas of the Americas. The authors report on an urban adult male patient with uncommon oral-cutaneous lesions proven to be histoplasmosis. Additional investigation revealed unnoticed HIV infection with CD4+ cell count of 7/mm3. The treatment was performed with amphotericin B, a 2065 mg total dose followed by itraconazole 200mg/daily plus antiretroviral therapy with apparent cure. Histoplasmosis is an AIDS-defining opportunistic disease process; therefore, its clinical diagnosis must drive full laboratory investigation looking for unnoted HIV-infection. © 2013 by Anais Brasileiros de Dermatologia.420-423engAcquired immunodeficiency syndromeAmphotericin BHistoplasmosisamphotericin B deoxycholateantiretrovirus agentitraconazoleadultbiopsycase reportCD4 lymphocyte countCD8+ T lymphocytehistopathologyhistoplasmosishumanHuman immunodeficiency virus infectionhuman tissuemalaisemalemouth examinationmouth lesionserodiagnosisvirus loadArtigo10.1590/abd1806-4841.20131812S0365-05962013000300420WOS:000320937800014Acesso aberto2-s2.0-848795648442-s2.0-84879564844.pdf878948045837755275281169255191429348918548022920