A cysteine peptidase inhibitor from the Orange tree (Citrus sinensis) inhibits periodontitis-induced hone loss by retaining osteoclasts at the macrophage stage. - Leguizamon, Natalia Da Ponte [UNESP]; Coletto-Nunes, Glaucia [UNESP]; Neo-Justino, Daniela Morilha; Schneider, Vanessa Karine; Boas Nogueira, Andressa Vilas [UNESP]; Molon, Rafael Scaf [UNESP]; Da Silva, Flavio Henrique; Da Costa Fuentes, Andrea Soares; Lerner, Ulf Holger; Cirelli, Joni Augusto [UNESP]; Chaves Souza, Pedro Paulo [UNESP] (Wiley-Blackwell, 2018)