Holland, Roberto [UNESP]Otoboni Filho, José Arlindo [UNESP]Souza, Valdir de [UNESP]Nery, Mauro Juvenal [UNESP]Bernabé, Pedro Feliciano Estrada [UNESP]Dezan Júnior, Eloi [UNESP]2014-05-272014-05-271998-12-01Brazilian dental journal, v. 9, n. 2, p. 67-76, 1998.0103-6440http://hdl.handle.net/11449/65642The subject of this paper was to study the behavior of the periapical tissues of dogs' teeth after biopulpectomy and dressing with calcium hydroxide or a corticosteroid-antibiotic association, before root canal filling with zinc oxide eugenol (ZOE) or Sealapex sealers. The teeth were overinstrumented and dressed for 7 days before the root canal filling. The animals were sacrificed 180 days after treatment and the specimens were prepared for morphological analysis. Specimens treated with Sealapex presented a higher number of cases with biological closure than ZOE. When the root canals were filled with ZOE, better results were observed with the use of the Ca(OH)2 dressing.67-76engantiinfective agentantiinflammatory agentbiomedical and dental materialscalcium hydroxidecortisporinhydrocortisoneneomycinpolymyxin Bsalicylic acid derivativesealapexzinc oxide eugenolanimalcomparative studydogdrug combinationdrug effectendodonticsperiodontiumwound healingAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsCalcium HydroxideDogsDrug CombinationsHydrocortisoneNeomycinPeriapical TissuePolymyxin BPulpectomyRoot Canal IrrigantsSalicylatesWound HealingZinc Oxide-Eugenol CementArtigoAcesso aberto2-s2.0-0032233663668577131186189153346401593617218813777272581972