Elias, Gracieli P. [UNESP]Sassaki, Kikue T. [UNESP]Delbem, Alberto Carlos Botazzo [UNESP]Silva, Cristina Antoniali [UNESP]2014-05-272014-05-272008-02-01Clinical and Experimental Hypertension, v. 30, n. 2, p. 133-141, 2008.1064-19631525-6006http://hdl.handle.net/11449/70294The salivary activity in pups of spontaneously hypertensive rats (SHR) and Wistar (W) rats treated with atenolol during pregnancy, and lactation was evaluated. Atenolol's anti-hypertensive effect on the SHR rats was noticed from the beginning of treatment. Atenolol-treated SHR and Wistar rat pups showed a decrease in salivary gland weight, salivary flow, and protein concentration, with no alteration in salivary amylase activity. Atenolol's effect on salivary glands can interfere with oral health maintenance. Copyright © Informa Healthcare USA, Inc.133-141engAtenololSalivary glandsSpontaneously hypertensive rats (SHR)amylaseatenololanimal experimentanimal modelantihypertensive activitycontrolled studyenzyme activityfemalehealthhypertensionlactationmalenonhumanpregnancyratsalivary glandsalivationAdrenergic beta-AntagonistsAmylasesAnimalsFemaleHypertensionLactationMaleOrgan SizeOsmolar ConcentrationPregnancyPregnancy Complications, CardiovascularRatsRats, Inbred SHRRats, WistarSalivaSalivary GlandsSalivary ProteinsAtenolol reduces salivary activity in pups of spontaneously hypertensive and normotensive rats treated during pregnancy and lactationArtigo10.1080/10641960801931923Acesso restrito2-s2.0-3974916831766564335394938790000-0002-8159-4853