Murakami, M. T.Watanabe, L.Gava, L. M.Zela, S. P.Cintra, ACOArni, R. K.2014-05-202014-05-202003-10-01Acta Crystallographica Section D-biological Crystallography. Copenhagen: Blackwell Munksgaard, v. 59, p. 1813-1815, 2003.0907-4449http://hdl.handle.net/11449/21962Convulxin, an alphabeta C-type lectin, is a potent platelet activator isolated from the venom of the South American rattlesnake Crotalus durissus terrificus. It is a 26.5 kDa alphabeta heterodimer consisting of two homologous disulfide-linked chains. The crystals belong to space group I4, with unit-cell parameters a = b = 131.61, c = 121.85 Angstrom, and diffraction data were collected to 2.7 Angstrom. The structure was solved by molecular replacement and the asymmetric unit contains two alphabeta heterodimers, each of which forms a disulfide-linked cyclic alpha(4)beta(4) tetramer in the unit cell. These alpha(4)beta(4) tetramers are stacked to form a large solvent channel.1813-1815engArtigo10.1107/S0907444903016202WOS:000185451200018Acesso restrito91625089789458870000-0003-2460-1145