Oliveira, Joao Batista A.Mauri, Ana LuciaPetersen, Claudia G.Martins, Anice M. C.Cornicelli, JoaoCavanha, MarioPontes, Anaglória [UNESP]Baruffi, Ricardo L. R.Franco, Jose G.2014-05-202014-05-202007-03-01Journal of Assisted Reproduction and Genetics. New York: Springer/plenum Publishers, v. 24, n. 2-3, p. 67-75, 2007.1058-0468http://hdl.handle.net/11449/12053Purpose: to compare the efficacy of recombinant LH supplementation for controlled ovarian stimulation in recombinant FSH and GnRH-agonist protocol.Methods: Search strategies included on-line surveys of databases. The fixed effects model was used for odds ratio and effect size (weighted mean difference). Four trials fulfilled the inclusion criteria.Results: a fewer days of stimulation (p < 0.0001), a fewer total amount of r-FSH administered (p < 0.0001) and a higher serum estradiol levels on the day of hCG administration (p < 0.0001) were observed for the r-LH supplementation protocol. However, differences were not observed in number of oocyte retrieved, number of mature oocytes, clinical pregnancy per oocyte retrieval, implantation and miscarriage rates.Conclusions: more randomized controlled trials are necessary before evidence-based recommendations regarding exogenous LH supplementation in ovarian stimulation protocols with FSH and GnRH-agonist for assisted reproduction treatment can be provided.67-75engGnRH agonistrecombinant FSHrecombinant LHovarian stimulationArtigo10.1007/s10815-006-9095-4WOS:000245534400006Acesso restrito0514178654667684