Picchi, Douglas Gatte [UNESP]Altei, Wanessa Fernanda [UNESP]Saito, Mônica Sue [UNESP]Bolzani, Vanderlan da Silva [UNESP]Cilli, Eduardo Maffud [UNESP]2014-05-202014-05-202009-01-01Química Nova. Sociedade Brasileira de Química, v. 32, n. 5, p. 1262-1277, 2009.0100-4042http://hdl.handle.net/11449/25250Natural peptides are outstanding as the most promising macromolecules in the search for new drugs, especially those of cyclic nature. The higher plants revealed a very peculiar composition of their cyclic peptides, which distinguish themselves by a head-to-tail cyclization. It is possible to define two groups of cyclic peptides from plant biomass. Those called in this review as Eucyclopeptides formed by 2-12 amino acid, and Cyclotides considered as circular polypeptides, composed of 29-37 amino acid that retain three disulfides bridges in an arrangement known as cyclic cystine knot. Searching for plant peptides should form into a subject for scientific research in the forefront of great importance for bioprospecting natural products macromolecular.1262-1277porcyclic peptideseucyclopeptidescyclotidesArtigo10.1590/S0100-40422009000500033S0100-40422009000500033WOS:000269124800033Acesso abertoS0100-40422009000500033.pdf448408368525167394243467624604160000-0002-4767-0904