Damiani, D.Manna, T. D.Aquino, LGWAlves, F.Longatto, A.Kanamura, C. T.Setian, N.2015-03-182015-03-181995-07-01Tumori. Milan: Casa Editrice Ambrosiana, v. 81, n. 4, p. 273-277, 1995.0300-8916http://hdl.handle.net/11449/117827Aims mid background: We studied, retrospectively, 33 cases of adrenal tumors of children at the Pediatric Endocrinology Unit, Children's Institute, Sao Paulo State University Medical School, from 1975 to 1993. Ail patients had at least 2 years of follow-up with a few exceptions. Methods: Clinical follow-up data were correlated with histopathologic review, laboratory data and cell kinetic evaluation (based on detection of proliferating cell nuclear antigens). Results: With one exception, all the patients had presented signs of androgen production and had high levels of dehydro-epiandrosterone-sulfate. Tumor weight evaluation represented a good parameter of neoplasm evolution: of 19 cases weighing less than 250 g, 17 had no evidence of disease after surgery, and 2 had an unfavorable prognosis. Of 14 cases weighing more than 250 g, only 1 had no evidence of disease and 13 had an unfavorable evolution. Conclusions: Proliferating cell nuclear antigen (PCNA) was not helpful to evaluate adrenal neoplasm evolution: our study did not show any correlation between PCNA score and prognosis.273-277engADRENAL NEOPLASMSPROLIFERATING CELL NUCLEAR ANTIGENCELL KINETICSPEDIATRIC NEOPLASMSENDOCRINOLOGIC NEOPLASMSArtigoWOS:A1995TA49900012Acesso restrito