Shimizu, M. T. [UNESP]Jorge, A. O C [UNESP]Unterkircher, C. S. [UNESP]Fantinato, V. [UNESP]Paula, C. R. [UNESP]2014-05-272014-05-271995-01-01Journal of Medical and Veterinary Mycology, v. 33, n. 1, p. 27-31, 1995.0268-1218http://hdl.handle.net/11449/64552The production of hyaluronidase and chondroitin sulphatase by Candida albicans, Candida tropicalis, Candida parapsilosis, Candida guilliermondii and Candida krusei was investigated using a complex culture medium (Sabouraud glucose agar) and a chemically defined medium. Among the 63 C. albicans isolates tested, 61 (97.8%) were found to be hyaluronidase and chondroitin sulphatase producers; one isolate produced only chondroitin sulphatase and one other was unable to produce either enzyme. The second major hyaluronidase and chondroitin sulphatase producing species was C. tropicalis followed by C. guilliermondii, C. parapsilosis and C. krusei. Among the C. albicans isolates tested no relation between the source of isolation and the amount of hyaluronidase and chondroitin sulphatase produced was found.27-31engchondrosulfatasehyaluronidaseunclassified drugcandida albicanscandida guilliermondiicandida kruseicandida parapsilosiscandida tropicaliscontrolled studyculture mediumenzyme synthesisnonhumanCandidaCandidiasis, OralCarrier StateChondroitinsulfatasesCulture MediaHumanHyaluronoglucosaminidaseSpecies SpecificitySupport, Non-U.S. Gov'tArtigo10.1080/02681219580000061Acesso restrito2-s2.0-00290617870053567153623569