Machado, Adriana Gadotti [UNESP]Komiyama, Edson Yukio [UNESP]Santos, Silvana Soléo Ferreira DosJorge, Antonio Olavo Cardoso [UNESP]Brighenti, Fernanda Lourenção [UNESP]Koga-ito, Cristiane Yumi [UNESP]2021-07-142021-07-142011-08Journal of Applied Oral Science. Bauru, SP, Brazil: Faculdade De Odontologia De Bauru - USP, v. 19, n. 4, p. 384-387, 2011.1678-77571678-7765http://hdl.handle.net/11449/213084Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37ºC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.384-387engCandida albicansCell adhesionPeriodontitisVirulence factorsArtigo10.1590/S1678-77572011005000014S1678-77572011000400015Acesso abertoS1678-77572011000400015.pdf65435631614034210000-0002-2416-2173