Alvarez, C.Ramirez-Campillo, R.Martinez-Salazar, C.Mancilla, R.Flores-Opazo, M.Cano-Montoya, J.Ciolac, E. G. [UNESP]2018-12-112018-12-112016-08-01International Journal of Sports Medicine, v. 37, n. 9, p. 723-729, 2016.1439-39640172-4622http://hdl.handle.net/11449/168889Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5±1.8 years; BMI=30.5±0.6 kg/m2) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3±1.4%), HbA1c (12.8±1.1%), systolic blood pressure (3.7±0.5 mmHg), HDL-cholesterol (21.1±2.8%), triglycerides (17.7±2.8%), endurance performance (9.8±1.0%), body weight (2.2±0.3%), BMI (2.1±0.3%), waist circumference (4.0±0.5%) and subcutaneous fat (18.6±1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.723-729engblood pressurebody compositionendurance performanceglycemic controlhigh-intensity interval exercisetype 2 diabetes mellitusArtigo10.1055/s-0042-104935Acesso restrito2-s2.0-84982706036