Hara, Anderson TakeoMagalhães, Cláudia Silami deCampos Serra, MônicaRodrigues Júnior, Antonio Luiz2014-05-272014-05-272002-12-01Journal of Dentistry, v. 30, n. 5-6, p. 205-212, 2002.0300-5712http://hdl.handle.net/11449/67033Objective. The aim of this in vitro study was to evaluate the interaction between two sources of fluoride (restorative systems and dentifrices) in inhibiting artificial root caries development. Methods. One hundred and eighty tooth segments were embedded in polyester resin, and sanded flat. Cylindrical cavities 1.0 mm-deep and 1.5 mm-diameter were prepared in root dentin and randomly restored by fluoride-containing restorative systems: Ketac-fil/Espe (Ke), Fuji II LC/GC Corp (Fj), F2000/3M (F2), Surefil/Dentsply (Su) or a control: Filtek Z250/3M (Z2). Ten experimental groups were made to test the association among the five restorative systems and two dentifrices: with F - (Sensodyne Baking Soda) or without F- (Sensodyne Original) (n = 18). After surface polishing, a 1 mm-wide margin around the restorations was demarcated and initial dentin surface Knoop microhardness values (KHNi) were obtained. The specimens were submitted to a pH-cycling model, and to applications of slurries of dentifrice. Afterwards the final dentin surface Knoop microhardness values (KHNf) were measured. Results. The differences between KHNi and KHNf, and the covariate KHNi were considered by the ANCOVA and Tukey's test (α = 0.05). The interaction between restorative system and dentifrice was statistically significant (p = 0.0026). All restorative systems provided some protection against artificial caries challenge when associated with the fluoride-containing dentifrice treatment. The means (standard deviation) of reductions in Knoop hardness values for systems associated with the fluoride-containing dentifrice were: Ke: 40.0(1.02)a, Fj: 41.9(1.02)b, F2: 43.3(1.04)c, Su: 43.5(1.00)c, Z2: 44.0(1.02)c; and with the non-fluoride-containing dentifrice were: Ke: 42.9(1.02)a, Fj: 44.7(1.01)b, F2: 45.2(1.09)bc, Su: 46.0(0.99)c, Z2: 46.6(0.99)c (statistical differences were expressed by different letters). Conclusion. The cariostatic effect shown by the fluoride-containing dentifrice could enhance that shown by Ketac-fil and Fuji II LC, and could mask that shown by F2000. © 2002 Elsevier Science Ltd. All rights reserved.205-212engDentifriceFluorideRestorative materialRoot cariesanticaries agentfluoridepolyestertoothpastebiomedical and dental materialscompomerF2000 cementFiltek Z250Fuji II LC cementglass ionomerKetac FilKetac-Filmaleic acid derivativenitratephosphateresinresin cementSureFil packable compositebiopolishingdentinin vitro studymeasurementpHreviewstatistical analysistoothanalysis of variancechemistryclinical trialcontrolled clinical trialcontrolled studydental cariesdental surgerydrug combinationdrug effecthardnesshumanrandomized controlled trialstatisticstooth brushingtooth rootultrastructureAnalysis of VarianceCariostatic AgentsCompomersComposite ResinsDental MaterialsDental PolishingDental Restoration, PermanentDentifricesDentinDrug CombinationsFluoridesGlass Ionomer CementsHardnessHumansHydrogen-Ion ConcentrationMaleatesNitratesPhosphatesResin CementsResins, SyntheticRoot CariesStatisticsTooth RootArtigo10.1016/S0300-5712(02)00017-9WOS:000179763700003Acesso restrito2-s2.0-15944408312