Capelozza Boaventura, Juliana Maria [UNESP]Bertolini, Marcio Jose [UNESP]Padovani, Gislaine Cristina [UNESP]Brancini de Oliveira, Maria Rita [UNESP]Zaghete, Maria Aparecida [UNESP]de Oliveira Junior, Osmir Batista [UNESP]de Andrade, Marcelo Ferrarezi [UNESP]2014-05-202014-05-202012-07-01Dental Materials Journal. Tokyo: Japanese Soc Dental Materials Devices, v. 31, n. 4, p. 583-592, 2012.0287-4547http://hdl.handle.net/11449/16191The present work seeks to evaluate the biocompatibility of experimental glass ionomer cements (GIC) prepared from niobium-calcium fluoro-alumino-silicate glass powder and two commercial GICs. The GICs were implanted into the subcutaneous connective tissue of sixty rats. The rats were sacrificed during four varying time periods: 7, 15, 30, and 60 days and histopathological examinations were then performed. The Kruskal-Wallis test was performed to evaluate any significant differences between the materials. Additionally, multiple comparisons of the mean rank were also carried out using the Dunn test (p<0.05). No significant differences were observed that one GIC was superior to the other. The tissue response for all of the GICs tested was similar in all the periods examined.583-592engHistocompatibilityConnective tissueGlass ionomer cementsInflammationArtigo10.4012/dmj.2011-235WOS:000309250600011Acesso aberto