Lack of lung tissue and systemic accumulation after consecutive daily aerosols of amikacin in ventilated piglets with healthy lungs - Ferrari, Fabio [UNESP]; Lu, Qin; Coriat, Pierre; Petitjean, Olivier; Louchahi, Kamel; Goldstein, Ivan; Nieszkowszka, Ania; Elman, Marilia; Marquette, Charles-Hugo; Rouby, Jean-Jacques; Lechat, Philippe; Aymard, Guy; et al. (Wolters Kluwer, 2003)
Keywords: amikacin; aerosol; animal experiment; animal tissue; area under the curve; artificial ventilation; drug absorption; drug accumulation; drug blood level; drug tissue level; lung parenchyma; nonhuman; priority journal; swine; Administration, Inhalation; Aerosols; Amikacin; Anesthesia; Animals; Anti-Bacterial Agents; Area Under Curve; Lung; Respiration, Artificial; Swine; Tissue Distribution