Alves, A.Gontijo, AMDCSalvadori, Daisy Maria Favero [UNESP]Rocha, Noeme Sousa [UNESP]2014-05-202014-05-202004-05-01Veterinary Pathology. Lawrence: Amer Coll Vet Pathologist, v. 41, n. 3, p. 299-301, 2004.0300-9858http://hdl.handle.net/11449/13646Considering the high incidence of dogs with acute bacterial cystitis (BC) and the relationship among inflammation, genotoxicity, and carcinogenesis, we conducted a case-control study comparing the frequency of deoxyribonucleic acid (DNA) lesions assessed by the comet assay between disease-free animals (13 males and 13 females) and cytology-confirmed cases of acute BC (12 males and 12 females), which was mainly caused by Staphylococcus sp. (40%) and Escherichia coli (35%). The results show no increase in DNA damage in cells obtained by bladder washings and no influence of age, sex, and breed due to acute BC. In conclusion, DNA damage was seemingly not associated with the infection by specific bacteria.299-301engArtigo10.1354/vp.41-3-299WOS:000221344700018Acesso restrito60777359184692840000-0002-8188-8149