Felippe de Souza, J. A MCaetano, M. A L [UNESP]Yoneyama, Takashi2014-05-272014-05-272003-11-07Proceedings of the American Control Conference, v. 2, p. 1188-1193.0743-1619http://hdl.handle.net/11449/67471Here the results for CD4+T cells count and the viral load obtained from HIV sero-positive patients are compared with results from numerical simulations by computer. Also, the standard scheme of administration of drugs anti HIV (HAART schemes) which uses constant doses is compared with an alternative sub-optimal teatment scheme which uses variable drug dosage according to the evolution of a quantitative measure of the side effects. The quantitative analysis done here shows that it is possible to obtain, using the alternative scheme, the same performance of actual data but using variable dosage and having fewer side effects. Optimal control theory is used to solve and also to provide a prognosis related to the strategies for control of viraemia.1188-1193engAIDSDirect methodOptimizationTreatmentComputer simulationDrug dosagePatient treatmentProblem solvingVirusesSub-optimal schemeControl theoryTrabalho apresentado em evento10.1109/ACC.2003.1239749Acesso aberto2-s2.0-0142169391