Ruano, RodrigoRamalho, Alan SaitoMoraes de Freitas, Rogerio CaixetaDuarte Bonini Campos, Juliana Alvares [UNESP]Lee, WesleyZugaib, Marcelo2014-05-202014-05-202012-11-01Journal of Ultrasound In Medicine. Laurel: Amer Inst Ultrasound Medicine, v. 31, n. 11, p. 1731-1739, 2012.0278-4297http://hdl.handle.net/11449/16820Objectives-The purpose of this study was to predict perinatal outcomes using fetal total lung volumes assessed by 3-dimensional ultrasonography (3DUS) in primary pleural effusion.Methods-Between July 2005 and July 2010, total lung volumes were prospectively estimated in fetuses with primary pleural effusion by 3DUS using virtual organ computer-aided analysis software. The first and last US examinations were considered in the analysis. The observed/expected total lung volumes were calculated. Main outcomes were perinatal death (up to 28 days of life) and respiratory morbidity (orotracheal intubation with mechanical respiratory support >48 hours).Results-Twelve of 19 fetuses (63.2%) survived. Among the survivors, 7 (58.3%) had severe respiratory morbidity. The observed/expected total lung volume at the last US examination before birth was significantly associated with perinatal death (P < .01) and respiratory morbidity (P < .01) as well as fetal hydrops (P < .01) and bilateral effusion (P = .01).Conclusions-Fetal total lung volumes may be useful for the prediction of perinatal outcomes in primary pleural effusion.1731-1739engfetal hydrothoraxfetal lungfetal pleural effusionfetal therapylung volumepulmonary hypoplasiaultrasonographyArtigoWOS:000310653000005Acesso restrito