Mondelli, MelinaBrune, VernicaBorthagaray, GracielaEllena, JavierNascimento, Otaciro R.Leite, Clarice Q. [UNESP]Batista, Alzir A.Torre, Maria H.2014-05-202014-05-202008-02-01Journal of Inorganic Biochemistry. New York: Elsevier B.V., v. 102, n. 2, p. 285-292, 2008.0162-0134http://hdl.handle.net/11449/40337The synthesis, structural characterization, voltammetric experiments and antibacterial activity of [Ni(sulfisoxazole)(2)(H2O)(4)] center dot 2H(2)O and [Ni(sulfapyridine)(2)] were studied and compared with similar previously reported copper complexes. [Ni(sulfisoxazole)(2)(H2O)(4)] center dot 2H(2)O crystallized in a monoclinic system, space group C2/c where the nickel ion was in a slightly distorted octahedral environment, coordinated with two sulfisoxazole molecules through the heterocyclic nitrogen and four water molecules. [Ni(sulfapyridine)(2)] crystallized in a orthorhombic crystal system, space group Pnab. The nickel ion was in a distorted octahedral environment, coordinated by two aryl amine N from two sulfonamides acting as monodentate ligands and four N atoms (two sulfonamidic N and two heterocyclic N) from two different sulfonamide molecules acting as bidentate ligands. Differential pulse voltammograms were recorded showing irreversible peaks at 1040 and 1070 mV, respectively, attributed to Ni(II)/Ni(III) process. [Ni(sulfisoxazole)(2)(H2O)(4)] center dot 2H(2)O and [Ni(sulfapyridine)(2)] presented different antibacterial behavior against Staphylococcus aureus and Escherichia coli from the similar copper complexes and they were inactive against Mycobacterium tuberculosis. (c) 2007 Elsevier B.V. All rights reserved.285-292engNi complexsulfonamidesantibacterial activityX-ray structureArtigo10.1016/j.jinorgbio.2007.09.001WOS:000253553000015Acesso restrito