Ribeiro, Erika M. de O.Lima, Luciano S.David, Jorge M.Vale, Ademir E. DoLopes, Lucia M.X. [UNESP]David, Juceni P.2014-05-272014-05-272013-05-01Phytochemistry Letters, v. 6, n. 2, p. 232-235, 2013.1874-39001876-7486http://hdl.handle.net/11449/75231A new tropane alkaloid, named the 7β-acetoxy-3β,6β- dibenzoyloxytropane (1), was isolated from a methanol extract of Erythroxylum rimosum O.E. Schulz leaves. Other known compounds were detected, including quercetin, kaempferol-3-O-α-l-arabinofuranoside, (+)-catechin, epicatechin, quercetin-3-O-α-arabinofuranoside, quercetin-3-O-α- arabinopyranoside, quercetin-3-O-β-arabinopyranoside, quercetin-3-β- glucopyranoside, kaempferol, quercetin-3-O-β-galactopyranoside, β-sitosterol, α-amyrin, β-amyrin, and the ester derivatives of these two amyrins. Compound 1 exhibited weak inhibition of acetylcholinesterase. Structural identification was performed using IR, ESIHRMS and one- and two-dimensional NMR data analyses and confirmed by comparison with literature data. © 2013 Phytochemical Society of Europe.232-235engAcetylcholinesterase inhibitionErythroxylaceaeErythroxylum rimosumFlavonoidsTriterpenesTropane alkaloid7beta acetoxy 3beta,6beta dibenzoyloxytropaneacetylcholinesterasealpha amyrinbeta amyrincatechinepicatechinErythroxylum rimosum extractester derivativeglucopyranosidekaempferolkaempferol 3 O alpha levo arabinofuranosidekaempferol derivativemethanolplant extractquercetin 3 beta glucopyranosidequercetin 3 O alpha arabinofuranosidequercetin 3 O alpha arabinopyranosidequercetin 3 O beta galactopyranosidequercetin derivativesitosteroltropane alkaloidunclassified drugcholinesterase inhibitioncontrolled studydrug structureelectrospray mass spectrometryenzyme inhibitionheteronuclear multiple bond correlationinfrared radiationnuclear magnetic resonanceplant leafpriority journalproton nuclear magnetic resonanceErythroxylumArtigo10.1016/j.phytol.2013.02.008WOS:000318271400017Acesso restrito2-s2.0-84875024992