Guinsburg, RuthBranco de Almeida, Maria FernandaCastro, Junia Sampel deSilveira, Rita C.Siqueira Caldas, Jamil Pedro deFiori, Humberto HolmerVale, Marynea Silva doSteffen Abdallah, Vania OlivettiMonteiro Bigelli Cardoso, Laura EmiliaAlves Filho, NavantinoMoreira, Maria ElisabethAcquesta, Ana LuciaLopes Ferrari, Ligia S.Bentlin, Maria Regina [UNESP]Venzon, Paulyne StadlerGoncalves Ferri, Walusa AssadMeneses, Jucille do AmaralDe Albuquerque Diniz, Edna MariaToledo Zanardi, Dulce MariaDos Santos, Cristina NunesBandeira Duarte, Jose LuizSantiago Rego, Maria Albertina2018-11-262018-11-262016-03-18Journal Of Maternal-fetal & Neonatal Medicine. Abingdon: Taylor & Francis Ltd, v. 29, n. 6, p. 1005-1009, 2016.1476-7058http://hdl.handle.net/11449/164700Objective: To analyze unfavorable outcomes at hospital discharge of preterm infants born at Brazilian public university centers.Methods: Prospective cohort of 2646 inborn infants with gestational age 23-33 weeks and birth weight 400-1499g, without malformations, born at 20 centers in 2012-2013. Unfavorable outcome was defined as in-hospital death or survival at hospital discharge with 1 major morbidities: bronchopulmonary dysplasia (BPD) at 36 corrected weeks, intraventricular hemorrhage (IVH) grades 3-4, periventricular leukomalacia (PVL) or surgically treated retinopathy of prematurity (ROP).Results: Among 2646 infants, 1390 (53%) either died or survived with major morbidities: 793 (30%) died; 497 (19%) had BPD; 358 (13%) had IVH 3-4 or PVL; and 84 (3%) had ROP. Logistic regression adjusted by center showed association of unfavorable outcome with: antenatal steroids (OR 0.70; 95%CI 0.55-0.88), C-section (0.72; 0.58-0.90), gestational age <30 (4.00; 3.16-5.07), being male (1.44; 1.19-1.75), small for gestational age (2.19; 1.72-2.78), 5th-min Apgar <7 (3.89; 2.88-5.26), temperature at NICU admission <36.0 degrees C (1.42; 1.15-1.76), respiratory distress syndrome (3.87; 2.99-5.01), proven late sepsis (1.33; 1.05-1.69), necrotizing enterocolitis (3.10; 2.09-4.60) and patent ductus arteriosus (1.69; 1.37-2.09).Conclusions: More than half of the VLBW infants born at public university level 3 Brazilian hospitals either die or survive with major morbidities.1005-1009engBronchopulmonary dysplasiaintraventricular hemorrhageneonatal mortalityperiventricular leukomalaciapreterm newborn infantretinopathy of prematurityvery low birth weight newborn infantArtigo10.3109/14767058.2015.1031740WOS:000366322400028Acesso aberto2559637400719543