Santana, Jeferson O.Freitas, Marcelo C. de [UNESP]Santos, Diana M. dosRossi, Fabricio E.Lira, Fabio S. [UNESP]Rosa-Neto, Jose C.Caperuto, Erico C.2018-11-262018-11-262018-08-08Frontiers In Physiology. Lausanne: Frontiers Media Sa, v. 9, 6 p., 2018.1664-042Xhttp://hdl.handle.net/11449/164499The purpose of this study was to investigate the effects of beta-alanine supplementation on a 10 km running time trial and lactate concentration in physically active adults. Sixteen healthy subjects were divided randomly into two groups: beta-alanine (n = 8) and placebo group (n = 8). The experimental group ingested 5 g/day of beta-alanine plus 1 g of resistant starch, and control group ingested 6 g of resistant starch, both for 23 days. Time to complete a 10-km running time trial and lactate concentration following the test were assessed at baseline and post 23 days. The running training program was performed three times per week on non-consecutive days (day 1: running 7 km; day 2: six sprints of 500 m at maximum speed with 2 min of recovery; day 3: running 12 km). The time to complete a 10-km running time trial decreased significantly only for the beta-alanine group (Pre = 3441 +/- 326.7, Post = 3209 +/- 270.5 s, p < 0.05). When analyzing the delta (Time post minus Time at baseline value) there was a statistically significant difference between the beta-alanine vs placebo group (-168.8 +/- 156.6 vs. -53.60 +/- 78.81 s, p = 0.007), respectively. In addition, the beta-alanine group presented lower blood lactate concentration after the 10-km test (beta-alanine: Pre = 8.45 +/- 1.94 vs. Post = 6.95 +/- 2.44 mmol/L; Placebo: Pre = 8.7 +/- 3.0 vs. Post = 10.8 +/- 2.5 mmol/L, p = 0.03). In conclusion, beta-alanine supplementation improved the 10-km running time trial and reduced lactate concentration in physically active adults.6engsport nutritionendurance trainingperformancesupplementationrunning exerciseArtigo10.3389/fphys.2018.01105WOS:000441067800002Acesso abertoWOS000441067800002.pdf