Crestani, Ariela M. [UNESP]Cipriano, Ana C. [UNESP]Nunes-de-Souza, Ricardo L. [UNESP]2018-12-112018-12-112018-01-01Behavioural Processes.1872-83080376-6357http://hdl.handle.net/11449/176208Aggressive interactions between conspecific animals have been used as a social stressor with ethological characteristics to study how social interactions can modulate animal's behavior. Here, a new protocol based on aggressive and non-aggressive interactions was developed to study how different social interactions can alter the behavioral profile of animals re-exposed to the context in which the interaction occurred. We used factor analysis to trace the behavioral profile of socially defeated and non-defeated mice when they were re-exposed to the apparatus [three interconnected chambers: home chamber, tunnel and surface area]; we also compared the behavior presented before (habituation) and 24 h after (re-exposure) the non-aggressive or aggressive interactions. A final factor analysis from defeated animals yielded 4 factors that represented 72.09% of total variance; whereas non-defeated animal's analysis was loaded with 5 factors that represented 85.46% of total variance. A 5-min non-aggressive interaction reduced the frequency of stretched attend behavior in the tunnel, whereas a single social defeat reduced time in the tunnel and increased time spent performing self-grooming in the home chamber without conditioning any other spatio-temporal and complementary measures. Together, these results suggest that different social interactions may modulate distinct behavioral profiles in animals when re-exposed to the context.engContextual conditioningContextual memorySelf-groomingSocial defeatArtigo10.1016/j.beproc.2018.04.010Acesso aberto2-s2.0-850457465002-s2.0-85045746500.pdf