Kawahara, Elisa Ito [UNESP]Pelegrino Bastos Maues, Nadine Helena [UNESP]Santos, Klinsmann Carolo dos [UNESP]Barbanera, Pedro Octavio [UNESP]Braga, Camila Pereira [UNESP]Henrique Fernandes, Ana Angelica [UNESP]2015-03-182015-03-182014-10-01Indian Journal Of Biochemistry & Biophysics. New Delhi: Natl Inst Science Communication-niscair, v. 51, n. 5, p. 365-371, 2014.0301-1208http://hdl.handle.net/11449/117668Caloric restriction, defined as a reduction in calorie intake below ad libitum, without malnutrition can have beneficial effects. In this study, we evaluated the impact of caloric restriction of 30 and 60% on calorimetric parameters and oxidative stress in cardiac tissue in rats. Rats were randomly divided into 3 groups (n = 8): 01 = control; G2 = rats exposed to dietary restriction of 30%; and G3 = rats exposed to dietary restriction of 60%. Energy restriction decreased final body weight, oxidation of carbohydrates and lipid, oxygen consumption (VO2), carbon dioxide production (VCO2), resting metabolic rate (RMR), but elevated respiratory quotient (RQ). 03 animals also displayed an imbalance in the oxidant/antioxidant system, as revealed by the decrease in the lipid hydroperoxide (LH) level and GSH-Px activity in heart tissue. In conclusion, dietary restriction decreased oxidative metabolism, as seen by the colorimetric profiles and controlled oxidative stress in cardiac tissue.365-371engCalorimetryNutritional parametersOxidative stressEnergy restrictionMyocardiumArtigoWOS:000346622100005Acesso restrito