Ponce, Daniela [UNESP]Zamoner, Welder [UNESP]Freitas, Fernanda Moreira [UNESP]Balbi, André [UNESP]Awdishu, Linda2019-10-062019-10-062019-03-01Peritoneal Dialysis International, v. 39, n. 2, p. 183-187, 2019.1718-43040896-8608http://hdl.handle.net/11449/187453Studies on vancomycin pharmacokinetics in acute kidney injury (AKI) patients on high-volume peritoneal dialysis (HVPD) are lacking. We studied the pharmacokinetics of intravenous (IV) vancomycin in AKI patients treated by HVPD who received a prescribed single IV dose of vancomycin (15 – 20 mg/kg total body weight) to determine the extent of vancomycin removal and to establish vancomycin dosing guidelines for the empirical treatment of AKI patients receiving HVPD. The application of 18 mg/kg vancomycin every 48 – 72 hours in AKI patients undergoing HVPD was required to maintain therapeutic concentrations.183-187engAKIsepsisArtigo10.3747/pdi.2018.00092Acesso restrito2-s2.0-85062832421