Salustiano, Eugenia Maria AssunçãoCampos, Juliana Alvares Duarte Bonini [UNESP]Ibidi, Silvia MariaRuano, RodrigoZugaib, Marcelo2022-04-292022-04-292012-01-01Revista da Associacao Medica Brasileira, v. 58, n. 5, p. 587-593, 2012.0104-4230http://hdl.handle.net/11449/227150Objective: To evaluate the association between Apgar scores of less than seven at five minutes (AS5min < 7) and antenatal factors and postnatal outcomes. Methods: A retrospective cohort and case-control study of 27,252 consecutive term newborns in a low risk obstetrical population between January 2003 and December 2010. Maternal and infant databases were reviewed from all cases with AS5min < 7 (n = 121; 0.4%) and 363 cases with AS5min ≥ 7 at 5 minutes who were randomly selected by a computer program. The main outcomes were neonatal death, newborn respiratory distress, need for orotracheal intubation and neonatal intensive care unit (NICU), and hypoxic-ischemic-encephalopathy. Results: After multiple regression analysis, repeated late decelerations on cardiotocography (OR: 2.4; 95% CI: 1.4-4.1) and prolonged second stage of labor (OR: 3.3; 95% CI: 1.3-8.3) were associated with AS5min < 7, as well as neonatal respiratory distress (OR: 3.0; 95% CI: 1.3-6.9), orotracheal intubation (OR: 2.5; 95% CI: 1.2-4.8), need for NICU (OR: 9.5; 95% CI: 6.7-16.8), and hypoxic-ischemicencephalopathy (OR: 14.1; 95% CI: 3.6-54.7). No other antenatal factors were associated with AS5min < 7 (p > 0.05). Conclusion: Repeated late decelerations and prolonged second stage of labor in the low-risk population are predictors of AS5min < 7, a situation associated with increased risk of neonatal respiratory distress, need for mechanical ventilatory support and NICU, and hypoxic-ischemic-encephalopathy. © 2012 Elsevier Editora Ltda. All rights reserved.587-593engApgar scoresAsphyxiaDeliveryHypoxic-ischemic-encephalopathyNeonatal mortalityTermResenha10.1016/s0104-4230(12)70254-32-s2.0-84875485804