Xavier, F. H.Silva, K. G.H.Farias, I. E.G.Morais, A. R.V.Alencar, E. N.Araújo, I. B.Oliveira, A. G. [UNESP]Egito, E. S.T.2022-04-282022-04-282012-01-01Journal of Drug Delivery Science and Technology, v. 22, n. 4, p. 367-372, 2012.1773-2247http://hdl.handle.net/11449/219833Copaiba oil, when used as anti-inflammatory and anti-infective agent, presents two major problems: i) low absorption and bioavailability and ii) an unpleasant taste. Once an appropriate emulsion was achieved, the samples were prepared using different surfactant binary mixtures to obtain a range of HLB values between 45 and 16.5. The HLB value of copaiba oil was 14.8; this system has been stable for more than one year, and the pseudo-ternary diagrams were useful to describe the component proportions. These results indicated that the copaiba oil emulsion might be a promising vehicle for topical delivery of drugs and active cosmetic ingredients.367-372engCopaiba oilEmulsionHydrophilic-lipophilic balancePseudo-ternary phase diagramStability analysisArtigo10.1016/s1773-2247(12)50061-42-s2.0-84865835486