Pagotto, Leonardo LibardiSpinola, Manuela Da Silva [UNESP]Nóbrega, Diego FigueiredoCury, Jaime AparecidoTenuta, Livia Maria Andaló2021-06-252021-06-252021-01-01Caries Research.1421-976X0008-6568http://hdl.handle.net/11449/206135Extracellular polysaccharides (EPS), mainly the insoluble ones, increase the cariogenicity of dental biofilm, but whether they interfere with the binding and retention of fluoride is unknown. EPS-rich (EPS+) and EPS-poor (EPS-) pellets of Streptococcus mutans were formed and treated with increasing fluoride concentrations (0, 0.1, 1, or 10 mM). A concentration-dependent fluoride binding was observed in both EPS-and EPS+ pellets, but the presence of EPS did not affect the retention of fluoride in the pellets. In conclusion, the data suggest that a matrix of dental biofilm rich in EPS does not affect fluoride retention in the biofilm.engArtigo10.1159/0005151152-s2.0-85103569522