Valera, Marcia Carneiro [UNESP]Maekawa, Lilian Eiko [UNESP]Chung, AdrianaOliveira, Luciane Dias deCarvalho, Claudio Antonio Talge [UNESP]Koga-Ito, Cristiane YumiJorge, Antonio Olavo Cardoso [UNESP]2014-05-272014-05-272012-07-01General Dentistry, v. 60, n. 4, 2012.0363-6771http://hdl.handle.net/11449/73425The results of the present study showed a significant decrease in the number of E. coli in root canals (first collection) after irrigation with castor oil extract during biomechanical preparation. All medications tested in this study were able to eliminate E. coli in root canals; however, they could not neutralize endotoxins completely.engantiinfective agentbiomedical and dental materialscalcium hydroxidecastor oilchlorhexidinechromogenic substratediagnostic agentendotoxinendotoxin, Escherichia colilipopolysaccharideplant extractpolymyxin Bsodium chloridetopical antiinfective agentbacterial loadcomparative studycontrolled clinical trialcontrolled studydrug antagonismdrug effectEscherichia colihumanLimulus lysate testmaterials testingmicrobiologyrandomized controlled trialtimetooth pulpAnti-Bacterial AgentsAnti-Infective Agents, LocalBacterial LoadCalcium HydroxideCastor OilChlorhexidineChromogenic CompoundsDental Pulp CavityEndotoxinsHumansLimulus TestLipopolysaccharidesMaterials TestingPlant ExtractsPolymyxin BRoot Canal IrrigantsSodium ChlorideTime FactorsArtigoAcesso restrito2-s2.0-8486407487147166766113303110053567153623569930460016658310065435631614034210000-0003-0987-55940000-0002-2416-2173