Aguiar, Andreo FernandoJanuário, Renata Selvatici BorgesJunior, Raymundo PiresGerage, Aline MendesPina, Fábio Luiz ChecheDo Nascimento, Matheus AmarantePadovani, Carlos Roberto [UNESP]Cyrino, Edilson Serpeloni2014-05-272014-05-272013-04-01European Journal of Applied Physiology, v. 113, n. 4, p. 987-996, 2013.1439-6319http://hdl.handle.net/11449/74900This study examined the effects of long-term creatine supplementation combined with resistance training (RT) on the one-repetition maximum (1RM) strength, motor functional performance (e.g., 30-s chair stand, arm curl, and getting up from lying on the floor tests) and body composition (e.g., fat-free mass, muscle mass, and % body fat using DEXA scans) in older women. Eighteen healthy women (64.9 ± 5.0 years) were randomly assigned in a double-blind fashion to either a creatine (CR, N = 9) or placebo (PL, N = 9) group. Both groups underwent a 12-week RT program (3 days week-1), consuming an equivalent amount of either creatine (5.0 g day-1) or placebo (maltodextrin). After 12 week, the CR group experienced a greater (P < 0.05) increase (Δ%) in training volume (+164.2), and 1RM bench press (+5.1), knee extension (+3.9) and biceps curl (+8.8) performance than the PL group. Furthermore, CR group gained significantly more fat-free mass (+3.2) and muscle mass (+2.8) and were more efficient in performing submaximal-strength functional tests than the PL group. No changes (P > 0.05) in body mass or % body fat were observed from pre- to post-test in either group. These results indicate that long-term creatine supplementation combined with RT improves the ability to perform submaximal-strength functional tasks and promotes a greater increase in maximal strength, fat-free mass and muscle mass in older women. © 2012 Springer-Verlag Berlin Heidelberg.987-996engAgingCreatineErgogenic aidMuscle strengthResistance trainingcreatineperformance enhancing substanceageagedanalysis of variancebody compositionBrazilcontrolled clinical trialcontrolled studydiet supplementationdouble blind proceduredrug effectfemalehumanmiddle agedmotor activitymuscle contractionmuscle strengthorgan sizephoton absorptiometryradiographyrandomized controlled trialresistance trainingsex differenceskeletal muscletimeAbsorptiometry, PhotonAge FactorsAgedAnalysis of VarianceBody CompositionDietary SupplementsDouble-Blind MethodFemaleHumansMiddle AgedMotor ActivityMuscle ContractionMuscle StrengthMuscle, SkeletalOrgan SizePerformance-Enhancing SubstancesResistance TrainingSex FactorsTime FactorsArtigo10.1007/s00421-012-2514-6WOS:000316124900019Acesso restrito2-s2.0-848762867278727897080522289