Teixeira, Marcos F. S. [UNESP]Dadamos, Tony R. L. [UNESP]2014-05-202014-05-202009-01-01Proceedings of The Eurosensors Xxiii Conference. Amsterdam: Elsevier B.V., v. 1, n. 1, p. 297-300, 2009.1876-6196http://hdl.handle.net/11449/6972An amperometric dipyrone sensor based on a polymeric nickel-salen (salen = N,N'-ethylenebis(salicydeneiminato)) film coated platinum electrode was developed. The sensor was constructed by electropolymerization of nickel-salen complex at a platinum electrode in acetonitrile/tetrabuthylamonium perchlorate by cyclic voltammetry. After cycling the modified electrode in a 0.50 mol L-1 KCl solution, the estimated surface concentration was found to be equal to 1.29 x 10(-9) mol cm(-2). This is a typical behavior of an electrode surface immobilized with a redox couple that can usually be considered as a reversible single-electron reduction/oxidation of the nickel(II)/nickel(III) couple. A plot of the anodic current versus the dipyrone concentration for chronoamperometry (potential fixed = +0.50 V) at the sensor was linear in the 4.7 x 10(-6) to 1.1 x 10(-4) mol L-1 concentration range and the concentration limit was 1.2 x 10(-6) mol L-1. The proposed electrode is useful for the quality control and routine analysis of dipyrone in pharmaceutical formulations.297-300engmodified electrodenickel-salen polymeramperometric detectiondipyrone analysisArtigo10.1016/j.proche.2009.07.074WOS:000275995600210Acesso abertoWOS000275995600210.pdf