Callera, João Carlos [UNESP]Saad, Wilson Abrão [UNESP]Camargo, Luiz Antonio de Arruda [UNESP]Renzi, Antonio [UNESP]Luca Junior, Laurival Antonio de [UNESP]Menani, José Vanderlei [UNESP]2014-05-272014-05-271994-02-14Neuroscience Letters, v. 167, n. 1-2, p. 153-155, 1994.0304-3940http://hdl.handle.net/11449/130733In the present experiments, we investigated a possible involvement of noradrenergic receptors of the lateral hypothalamus (LH) in the water intake and pressor response induced by cholinergic stimulation of the medial septal area (MSA) in rats. The cholinergic agonist carbachol (2 nmol) injected into the MSA induced water intake and pressor response. The injection of an α2-adrenergic agonist, clonidine (20 and 40 nmol), but not of an α1-adrenergic agonist, phenylephrine (80 and 160 nmol), into the LH inhibits the water intake induced by carbachol injected into the MSA. The injection of clonidine or phenylephrine into the LH produced no change in the MAP increase induced by carbachol injected into the MSA. The present results suggest that adrenergic pathways involving the LH are important for the water intake, but not for the pressor response, induced by cholinergic activation of the MSA. © 1994.153-155engAdrenergic receptorArterial pressureCholinergic receptorThirstWater intakeAlpha 1 adrenergic receptorAlpha 2 adrenergic receptorAlpha adrenergic receptor blocking agentAlpha adrenergic receptor stimulating agentCarbacholClonidinePhenylephrineAnimal experimentBlood pressureCholinergic systemControlled studyFluid intakeIntracerebral drug administrationLateral hypothalamusMaleNonhumanPriority journalRatSeptum nucleusAnimalBlood PressureCarbacholClonidineDrinkingHypothalamic Area, LateralMaleNeural PathwaysParasympathomimeticsPhenylephrineRatsRats, Inbred StrainsSeptum PellucidumSupport, Non-U.S. Gov'tSympathetic Nervous SystemArtigo10.1016/0304-3940(94)91050-2WOS:A1994MY13100037Acesso restrito2-s2.0-002822174565512369362956971023597870118105339253755971890