Santini, Alberto O. [UNESP]Pezza, Helena Redigolo [UNESP]Sequinel, Rodrigo [UNESP]Rufino, Jose L. [UNESP]Pezza, Leonardo [UNESP]2014-05-202014-05-202009-01-01Journal of The Brazilian Chemical Society. São Paulo: Soc Brasileira Quimica, v. 20, n. 1, p. 64-73, 2009.0103-5053http://hdl.handle.net/11449/26109The construction, evaluation and analytical application of a potentiometric sensor, namely, Pt vertical bar Hg vertical bar Hg(2)(Fur)(2)vertical bar Graphite, where Fur stands for 4-chloro-N-furfuryl-5-sulphamoyl-anthranilate ion, are described. This electrode has a linear dynamic range between 5.0 x 10(-7)-1.0 x 10(-2) mol L(-1) with a near-Nernstian slope of (-58.4 +/- 0.9) mV decade(-1) and a detection limit of 3.8 x 10(-7) mol L(-1). The potentiometric response is independent of the pH of the solution in the pH range 7.0-9.0. The electrode shows easy construction, low-cost, fast response time (within 10-20 s) and can be used for a period of 6 months without significant change in its performance characteristics. The proposed sensor displayed good selectivities over a variety of other anions (carboxylates and inorganic anions). Application of this potentiometric sensor for the furosemide determination in pharmaceuticals, urine, blood serum and commercial milk samples is reported.64-73eng4-cloro-N-furfuryl-5-sulphamoylanthranilate-sensitive electrodepotentiometrypharmaceuticalsurinehuman blood serumbovine milkArtigo10.1590/S0103-50532009000100012S0103-50532009000100012WOS:000262752400012Acesso abertoS0103-50532009000100012.pdf319212509836112159789085918535240000-0003-0197-7369