Silva, Suzane Ramos de [UNESP]Silva, Ana Paula Ferraz da [UNESP]Bacchi, Maura Moscardi [UNESP]Bacchi, Carlos Eduardo [UNESP]Oliveira, Deilson Elgui de [UNESP]2014-05-202014-05-202011-02-01Cancer Letters. Clare: Elsevier B.V., v. 301, n. 1, p. 85-94, 2011.0304-3835http://hdl.handle.net/11449/13043The present study aimed to evaluate the frequency of KSHV genotypes isolated from Kaposi sarcoma (KS) lesions in patients from Brazil. Fifty KS cases were evaluated. The most frequently detected viral genotypes were A (50.0%) and C (48.0%); the B genotype was isolated only in one case (2.0%). Noteworthy, there was a significant predominance of A genotypes in KS lesions from HIV-positive patients, whereas C genotypes were found mostly in the HIV-negative setting. This finding supports the hypothesis that distinct KSHV genotypes have a non-random distribution in KS, which might be attributable to unique biological properties. (C) 2010 Elsevier B.V. All rights reserved.85-94engKSHVHHV-8Kaposi sarcomaViral genotypingArtigo10.1016/j.canlet.2010.10.011WOS:000287108900010Acesso restrito5240998569868081