DeLucia, R.Planeta, Cleopatra da Silva [UNESP]Aizenstein, M. L.Scavone, C.2014-05-202014-05-201997-08-01General Pharmacology. Oxford: Pergamon-Elsevier B.V., v. 29, n. 2, p. 265-267, 1997.0306-3623http://hdl.handle.net/11449/355841. In the present study, we evaluated the role of repeated administration on conditioning place preference (CPP) induced by fencamfamine (FCF) in male rats.2. Repeated FCF (3.5 mg/kg) or saline once or daily for ten consecutive days enhanced sniffing du ration and decreased locomotion and rearing duration.3. At the 3.5 mg/kg dose, FCF produced a significant place-preference effect.4. Repeated exposures to FCF intensified its reinforcing properties.5. These results suggest that repeated FCF administration sensitizes its rewarding effects, as with other addictive substances. GEN PHARMAC 29;2:265-261, 1997. (C) 1997 Elsevier B.V.265-267engfencamfaminepsychostimulantsensitizationplace conditioningreinforcing effectArtigo10.1016/S0306-3623(96)00414-4WOS:A1997XM42500022Acesso restrito25147625452809420000-0002-1378-6327