Machado, C. S.M. [UNESP]Ruperto, N.Silva, C. H.M.Ferriani, V. P.L.Roscoe, I.Campos, L. M.A.Oliveira, S. K.F.Kiss, M. H.B.Bica, B. E.R.G.Sztajnbok, F.Len, C. A.Melo-Gomes, J. A.2022-04-282022-04-282001-01-01Clinical and Experimental Rheumatology, v. 19, n. 4 SUPPL. 23, 2001.0392-856Xhttp://hdl.handle.net/11449/224219We report the cross-cultural adaptation and validation into Brazilian-Portuguese of the parent's version of two health related quality of life instruments. The Childhood Health Assessment Questionnaire (CHAQ) is a disease specific health instrument that measures functional ability in daily living activities in children with juvenile idiopathic arthritis (JIA). The Child Health Questionnaire (CHQ) is a generic health instrument designed to capture the physical and psychosocial well-being of children regardless the underlying disease. The Brazilian CHAQ was revalidated, while the CHQ has been derived from the Portuguese version. A total of 471 subjects were enrolled: 157 patients with JIA (27% systemic onset, 38% polyarticular onset, 9% extended oligoarticular subtype, and 26% persistent oligoarticular subtype) and 314 healthy children. The CHAQ discriminated clinically healthy subjects from JIA patients, with the systemic, polyarticular and extended oligoarticular subtypes having a higher degree of disability, pain, and lower overall well-being scores when compared to their healthy peers. Also the CHQ discriminated clinically healthy subjects from JIA patients, with the systemic onset, polyarticular onset and extended oligoarticular subtypes having a lower physical and psychosocial well-being score when compared to their healthy peers. In conclusion the Brazilian versions of the CHAQ-CHQ are reliable and valid tools for the combined physical and psychosocial assessment of children with JIA. © Copyright Clinical and Experimental Rheumatology 2001.engBrazilian Child Health Questionnaire (CHQ)Brazilian Childhood Health Assessment Questionnaire (CHAQ)Cross cultural adaptation and psychometric evaluationHealth related quality of lifeHealthy childrenJuvenile idiopathic arthritis (JIA)Artigo2-s2.0-0035405644