Barraviera, Silvia Regina Catharino Sartori [UNESP]Kiy, Y.Dillon, N. L.Marques, Silvio Alencar [UNESP]Lastoria, Joel Carlos [UNESP]Curi, P. R.2014-05-272014-05-271990-12-01Anais Brasileiros de Dermatologia, v. 65, n. 6, p. 293-297, 1990.0365-0596http://hdl.handle.net/11449/64043A late survey of the renal function was performed in eighteen patients with paracoccidioidomycosis treated with amphotericin B, according to the glomerular filtration rate (RFG). The method was compartment analysis by single injection using EDTA Cr51, determined by its 'half biological life' and dosages of blood urea nitrogen and creatinine. The patients were seventeen males and one female. They were from 22 to 76 years old. Ten of these patients received 2 g of amphotericin B and eight of them received 4 g. There were no expressive difference between the two groups, taking into account age, dose in mg/kg of weight/day, time of conclusion of the treatment, urea, creatinine, glomerular filtration was smaller than the normal, and average of the half biological life of the EDTA Cr51 was large than the normal. The achieved results permitted us to consider that the amphotericin B determines deficit of renal function. However, by the present study, it hasn't been possible to affirm if the modifications are definitive.293-297poramphotericin bclinical articleglomerulus filtration ratehumankidney functionsouth american blastomycosisArtigoAcesso restrito2-s2.0-002560306187894804583775529531498781164017