Isolation and structure elucidation of two new flavonoid glycosides from the infusion of Maytenus aquifolium leaves. Evaluation of the antiulcer activity of the infusion

Vilegas, Wagner [UNESP]Sanommiya, M.Rastrelli, L.Pizza, C.2014-05-202014-05-201999-02-01Journal of Agricultural and Food Chemistry. Washington: Amer Chemical Soc, v. 47, n. 2, p. 403-406, 1999.0021-8561http://hdl.handle.net/11449/34001Droplet countercurrent chromatography and high-performance liquid chromatography fractionation of the aqueous infusion from Maytenus aquifolium Martius leaves afforded two flavonoid tetrasaccharides: quercetin 3-O-alpha-L-rhamnopyranosyl(1-->6)-O-[beta-D-glucopyranosyl(1-->3)-O-alpha-L-rhamnopranosyl( 1-->2)-O-beta-D-galactopyranoside and kaempferol 3-O-alpha-L-rhamnopyranosyl(1-->6)-O-[beta-D-glucopyranosyl( 1-->3)-O-alpha-L-rhamnopyranosy(1-->2-2)-O-beta-D-galactopyranoside. All structures were elucidated by spectroscopic methods. Pharmacological essays of the infusion showed antiulcer activity in rats.403-406engMaytenus aquifolium MartiusCelastraceaeespinheira santainfusionantiulcer activityflavonoid glycosides1D and 2D NMRIsolation and structure elucidation of two new flavonoid glycosides from the infusion of Maytenus aquifolium leaves. Evaluation of the antiulcer activity of the infusionArtigo10.1021/jf980114iWOS:000078698500008Acesso restrito79278772243268370000-0003-3032-2556