Costa, Anna C.B.P. [UNESP]Pereira, Cristiane A. [UNESP]Junqueira, Juliana Campos [UNESP]Jorge, Antonio O.C. [UNESP]2014-05-272014-05-272013-07-17Virulence, v. 4, n. 5, p. 391-399, 2013.2150-55942150-5608http://hdl.handle.net/11449/75997The Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. Therefore, the study of experimentally induced oral candidiasis in rats and mice is useful to clarify the etiopathology of this condition, improve diagnosis, and search for new therapeutic options because the disease process in these animals is similar to that of human candidiasis lesions. Here, we describe and discuss new studies involving rat and mouse models of oral candidiasis with respect to methods for inducing experimental infection, methods for evaluating the development of experimental candidiasis, and new treatment strategies for oral candidiasis. © 2013 Landes Bioscience.391-399engCandida albicansMurine modelOral candidiasisOral cavityamphotericin Bdexamethasonefarnesolfluconazolelactoferrintetracyclinebacterial colonizationcolony forming unitconfocal laser microscopydisease severityepithelium hyperplasiagene expressionhistopathologyimmunizationimmunocompromised patientmuscle cellnonhumanphotodynamic therapyrisk factorSprague Dawley ratthrushtongueWistar ratArtigo10.4161/viru.25199WOS:000323324200007Acesso aberto2-s2.0-848800785842-s2.0-84880078584.pdf0322020541055900