Leonardo, Mário RobertoSalgado, Antônio Albertoda Silva, Léa AssedTanomaru Filho, Mário2014-05-272014-05-272003-01-01Pesquisa odontologica brasileira = Brazilian oral research, v. 17, n. 1, p. 69-74, 2003.1517-7491http://hdl.handle.net/11449/67168The aim of this study was to evaluate the apical and periapical repair after root canal treatment of dogs' teeth with pulp necrosis and chronic periapical lesion using different root canal sealers. After periapical lesion induction, forty-four root canals of 3 dogs were submitted to biomechanical preparation using 5.25% sodium hypochlorite as an irrigating solution. A calcium hydroxide dressing (Calen PMCC) was applied for 15 days and the root canals were filled using the lateral condensation technique with gutta-percha points and Sealapex, AH Plus or Sealer Plus for sealing. After 180 days, the animals were sacrificed by anesthetic overdose and the obtained histological sections were stained with hematoxylin-eosin for optical microscopic analysis of the apical and periapical repair. The groups filled with Sealapex and AH Plus had better histological repair (p < 0.05) than the group filled with Sealer Plus, that had unsatisfactory results.69-74engbiomaterialbiomedical and dental materialscalcium hydroxideepoxy resinroot canal filling materialanimalcomparative studydogdrug combinationdrug effectendodonticsevaluationfemalemaleperiodontiumstandardtooth periapical diseasetooth pulpwound healingAnimalsBiocompatible MaterialsCalcium HydroxideDental Pulp CavityDogsDrug CombinationsEpoxy ResinsFemaleMalePeriapical AbscessPeriapical PeriodontitisPeriapical TissueRoot Canal Filling MaterialsRoot Canal IrrigantsRoot Canal ObturationWound HealingArtigo10.1590/S1517-74912003000100013S1517-74912003000100013Acesso aberto2-s2.0-01421212712-s2.0-0142121271.pdf2665211298584751