Santos, Wilney de Jesus R.Sousa, Aline L.Sotomayor, Maria Del Pilar Taboada [UNESP]Damos, Flavio S.Tanaka, Sonia Maria C. N.Kubota, Lauro T.Tanaka, Auro A.2014-05-202014-05-202009-01-01Journal of The Brazilian Chemical Society. São Paulo: Soc Brasileira Quimica, v. 20, n. 6, p. 1180-1187, 2009.0103-5053http://hdl.handle.net/11449/40268The construction of an amperometric sensor for phenolic compounds using a carbon paste electrode modified with manganese phthalocyanine and histidine is reported. Under optimized conditions, at 0 mV vs Ag/AgCl in 0.1 mol dm(-3) phosphate buffer solutions (pH 7.0) containing 250 mu mol dm(-3) H2O2, a linear response for catechol from 20 up to 130 mu mol dm(-3) was obtained with a sensitivity of 0.56 (+/- 0.02) mu A dm(3) mu mol(-1) cm(-2). The detection limit was 1.1 mu mol dm(-3) and the response time was 2 s. The sensor presented stable response during 40 successive determinations. The repeatability, evaluated in terms of relative standard deviation, was 3.6% for n = 5 and [catechol] = 10 mu mol dm(-3). The sensor responses for other phenolic compounds were also investigated in details. Finally, the applicability of the sensor was tested in a pharmaceutical containing dopamine and the results compared favorably with those obtained with the official method.1180-1187engmanganese phthalocyaninephenolic compoundamperometric sensorArtigo10.1590/S0103-50532009000600025S0103-50532009000600025WOS:000268336800025Acesso abertoS0103-50532009000600025.pdf2933194342093387