Schellini, Silvana Artioli [UNESP]Xavier, Adriana P. [UNESP]Hoyama, Érika [UNESP]Rossa, Romualdo [UNESP]Pellizon, Cláudia [UNESP]Marques, Mariângela Esther Alencar [UNESP]Padovani, Carlos Roberto [UNESP]2014-05-272014-05-272002-08-23Orbit, v. 21, n. 3, p. 189-193, 2002.0167-6830http://hdl.handle.net/11449/66959PURPOSE: Gelatinous polyethylene (GP) has been used as an orbital implant to evaluate volume maintenance and tissue reaction in the anophthalmic socket in a rabbit model. METHODS: Twenty-eight Norfolk white rabbits underwent unilateral evisceration with placement of 2ml GP (GP group - 16 animals) or 2ml 0.9% sodium chloride solution (Control group - 12 animals). Animal behavior, postoperative tissue response and socket conditions were evaluated. The animals were sacrificed at 7, 15, 30 and 60 days after the surgery and the bulbs were enucleated; volume maintenance and histopathological evaluation were done in the enucleated bulbs. The results were submitted to statistical analysis. RESULTS: All animals showed normal behavior. The orbital volume maintenance was better in the GP group. Histopathology in the GP animals showed mild tissue inflammation throughout the evaluation period and a thin pseudocapsule formation surrounding the orbital implant material. CONCLUSION: The clinical findings, good orbital volume maintenance and mild inflammatory tissue response make GP a good choice to replace the lack of volume in anophthalmic socket reconstruction.189-193engAnophthalmic socketGelatinous polyethyleneHistopathologyOrbital volumeRabbitsSocket reconstructionpolyethylenesodium chlorideanimal experimentanimal tissueanophthalmiacontrolled studyenucleationeviscerationgelhistopathologyimplantinflammationnonhumanrabbitstatistical analysisAnimalBiocompatible MaterialsComparative StudyEye EnucleationGelatinModels, AnimalOrbitOrbital ImplantsPolyethylenesProsthesis ImplantationRandom AllocationTreatment OutcomeArtigo10.1076/orbi.21.3.189.7174Acesso restrito2-s2.0-0036023717942024910083549287278970805222897528116925519142