Calixto, Giovana [UNESP]Bernegossi, Jessica [UNESP]Fonseca-Santos, Bruno [UNESP]Chorilli, Marlus [UNESP]2015-03-182015-03-182014-01-01International Journal Of Nanomedicine. Albany: Dove Medical Press Ltd, v. 9, p. 3719-3735, 2014.1178-2013http://hdl.handle.net/11449/117454Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they remain far from optimal. Currently, cancer research is focused on improving cancer diagnosis and treatment methods (oral cavity and oropharynx) nanotechnology, which involves the design, characterization, production, and application of nanoscale drug delivery systems. In medicine, nanotechnologies, such as polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, gold nanoparticles, hydrogels, cyclodextrin complexes, and liquid crystals, are promising tools for diagnostic probes and therapeutic devices. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for oral cancers.3719-3735engtargeted deliveryoral squamous cell carcinomaoral cancer treatmentArtigo10.2147/IJN.S61670WOS:000340169100002Acesso abertoWOS000340169100002.pdf