Debonsi, Hosana M.Miranda, Jose E.Murata, Afonso T.de Bortoli, Sergio A. [UNESP]Kato, Massuo J.Bolzani, Vanderlan da Silva [UNESP]Furlan, Maysa [UNESP]2014-05-202014-05-202009-01-01Pest Management Science. Chichester: John Wiley & Sons Ltd, v. 65, n. 1, p. 47-51, 2009.1526-498Xhttp://hdl.handle.net/11449/26055BACKGROUND: A dichloromethane-methanol extract of the seeds of Piper tuberculatum Jacq. (Piperaceae) and two isobutyl amides, 4,5-dihydropiperlonguminine (1) and pellitorine (2), which were isolated by chromatographic methods, were assayed for their lethality against the sugarcane borer Diatraea saccharalis F. (Lepidoptera: Pyralidae).RESULTS: Bioassays were carried out with fourth-instar caterpillars through topical application of test solutions to the dorsal surface of the prothorax, and dose-response correlations were determined. Significant insect mortalities were observed 24, 48 and 72 h after treatment at concentrations of >= 100 mu g insect(-1). The LD(50) and LD(90) values for compound 1 were 92.83 and 176.50 mu g insect(-1), and for compound 2 they were 91.19 and 184.56 mu g insect(-1).CONCLUSION: According to the LD(50) and LD(90) for compounds 1 and 2, it can be inferred that the values reflect an acute lethal response to both compounds, based on interaction(s) of the toxicants with a primary target or series of targets. Thus, the amides were demonstrated to have potential value in the control of the sugarcane borer. (C) 2008 Society of Chemical Industry47-51engPiper tuberculatumDiatraea saccharalissugarcane borerisobutyl amidesTrabalho apresentado em evento10.1002/ps.1643WOS:000262245900008Acesso aberto44840836852516731308042794786872