Berezoswski, A. T.Cunha, S. P.Dacosta, J. C.Bacchi, C. E.2014-05-202014-05-201994-10-01International Journal of Gynecology & Obstetrics. Clare: Elsevier Sci Ireland Ltd, v. 47, n. 1, p. 23-26, 1994.0020-7292http://hdl.handle.net/11449/31506Objective: the proposal was to study the presence of immunoglobulin A (IgA) in the chorioamniotic membrane of healthy postpartum women with premature rupture of the chorioamniotic membrane (FROM). Method: A single radial immunodiffusion technique was used to quantify the IgA in the chorioamniotic membrane tissues. Results: the level of IgA was approximately 10 times higher in patients whose membranes had been ruptured for > 10 h (24.58 mg/dl). These results were compared with those of a previously published study where the mean of amount of IgA was 2.52 mg/dl in membranes of patients with rupture < 10 h. Our results show that IgA began to rise after 10-15 h following rupture. Conclusion: Although more studies need to be performed our data indicate that the increasing IgA in our patients after 10 h of latency probably represents the beginning of an ascending colonization of bacteria which could be the source of future infection.23-26engIMMUNOGLOBULIN AFROMMEMBRANE RUPTURECHORIOAMNIOTIC MEMBRANEArtigo10.1016/0020-7292(94)90456-1WOS:A1994PN51000004Acesso restrito