Macarenco, Ricardo S.Oliveira, Deilson Elgui de [UNESP]2015-10-212015-10-212015-05-01American Journal Of Dermatopathology. Philadelphia: Lippincott Williams &wilkins, v. 37, n. 5, p. 53-56, 2015.0193-1091http://hdl.handle.net/11449/128378Angioinvasion/angiodestruction has been reported in a small subset of primary cutaneous anaplastic large-cell lymphomas (PCALCL). Recently, PCALCL with angioinvasive features and cytotoxic phenotype has been characterized as a variant associated with good clinical outcomes despite worrisome histopathologic features. We report a case of PCALCL with angioinvasive features and cytotoxic phenotype associated with reparative changes on the wall of medium-sized vessels involved by the neoplasm, including intimal fibroblastic proliferation and luminal obliteration. This vascular pattern, although previously unreported in PCALCL, is in accordance with the indolent behavior observed in this entity and provides a further link with lymphomatoid papulosis type E.53-56engPrimary cutaneous anaplastic large-cell lymphomaCD30(+) lymphoproliferative disorderAngiocentric lymphomaAngioinvasive lymphomaCutaneous lymphomaCytotoxic phenotypeEndarteritis obliteransPseudovasculitisAngiodestructiveAngioinvasiveMuscular vesselsMedium-sized vesselsArtigo10.1097/DAD.0000000000000261WOS:000353346500001Acesso restrito5240998569868081